Will the WWE Championship change hands on SmackDown for the first time in four years?

Daniel Bryan and CM Punk compete in a rematch from WWE Over the Limit.

As an impactful week of WWE action continues to build steam, here are five things that the WWE Universe should keep an eye on during tonight's SmackDown on Syfy — beginning with the WWE Title picture.

For the first time in four years, the WWE Championship will be contested on a Friday night. When WWE Champion CM Punk emerges for action in Baton Rouge, La., he will put his illustrious title on the line against an angry, jilted monster in Kane, who has — willingly or not — become intertwined in the conflict between The Second City Saint and Daniel Bryan.

Surely primed to make the most of his title opportunity — in the type of high-pressure situation that he always thrives in — The Devil’s Favorite Demon is a serious threat to Punk’s nearly 200-day WWE Title reign. As the WWE Universe knows, the masked grappler is one of the most destructive forces the squared circle has ever known, and his ruthless aggression and thirst for vengeance can only work in his favor.

There’s an old saying about not waking a sleeping dog for fear of its bite. And now that The Big Red Monster seems to have become a pawn in the high stakes rivalry between Punk and Bryan, just how much more dangerous have they made their explosive situation? And could it all ultimately backfire with Kane walking out of SmackDown the new WWE Champion?

What can the WWE Universe expect from Sin Cara?

SmackDown: A special look at Sin Cara

Sin Cara, one of the most unique performers in SmackDown history, reenters a WWE ring for the first time since the 2011 Survivor Series. How will the Mexican-born high-flyer fair after a lengthy injury? Will there be any "ring rust"? Or will Sin Cara seamlessly hurl himself back into the SmackDown fray?

It’s hard to predict the unpredictable, which is a perfect descriptor for Sin Cara’s in-ring style, so the more pertinent questions may be: What will be the gravity-defying Superstar's intentions upon his return? And what new moves may he unveil in his aerial arsenal?

If his first run in WWE is any indication, the only thing to expect is the unexpected. But, at least one thing’s for sure: A well-rested, healthy Sin Cara is bound to bring a high-voltage performance to Friday night in a hurry.

What happens if Sheamus still won’t apologize to John Laurinaitis?

World Heavyweight Champion Sheamus will not apologize to John Laurinaitis.

It might as well be called "the shove heard ‘round the WWE Universe." When World Heavyweight Champion Sheamus ran into General Manager John Laurinaitis – accidently or not – on the May 21 edition of Raw SuperShow, he certainly incited the anger of a vengeful Big Johnny.

While The Great White has made it abundantly clear that he bows to no man, the Executive Vice President of Talent Relations has expressed his displeasure that Eve could not get The Celtic Warrior to apologize one week ago on SmackDown. Then on this Monday’s Raw SuperShow, the Irish Superstar overcame Mr. Laurinaitis’ legal counsel David Otunga with a fierce Brogue Kick.

Knowing the wrath the GM is capable of carrying out, the WWE Universe should brace itself for whatever the powerful executive may throw at the unremorseful World Heavyweight Champion next.

Will Big Show’s wrath spread to the blue brand?

Big Show unleashes his brutal side on Brodus Clay and WWE Tag Team Champions Kofi Kingston & R-Truth.

Big Show made it clear on Raw SuperShow that he no longer has any regard for his fellow competitors, laying waste to the undefeated Brodus Clay, Tag Team Champions Kofi Kingston & R-Truth and cornering US Champion Santino Marella. The terrifying World’s Largest Athlete may be the most dangerous he has ever been and is unquestionably capable of widespread destruction.

With nothing holding the giant back, it is reasonable to believe that his furious stomp through Raw’s roster may only be the beginning of his path of devastation. If so, will that road run through SmackDown, and who might be unlucky enough to cross the giant’s path?

Will Dolph Ziggler choose SmackDown as his outlet to Showoff?

Kofi Kingston & R-Truth defend their Tag Team Titles against Dolph Ziggler & Jack Swagger in a WWE Over the Limit rematch.

Dolph Ziggler has shown flashes of brilliance in his WWE career, proving that he’s a performer with a great skill set and, as the WWE Universe is well aware, he’s not afraid to let everyone within earshot know it. But now that The Showoff has expressed his frustration — stating Monday on Raw that he is "better" than the loss he suffered while teaming with Jack Swagger — Ziggler has laid down his own gauntlet. But, where will he look to answer the challenge?

Considering his thirst to prove himself, Ziggler is not the type of competitor who would wait a week to make his point. So, will he look to make noise tonight? Before moving to Raw, Ziggler thrived on SmackDown – including being crowned World Heavyweight Champion. Now, as he wants to prove his elite status, WWE.com would not be surprised if he looked to make a splash on Friday nights.